Could you please tell me if there is a standard as to how large the opening in a machine must be in order to carry out particle measurements.

By machine you surely mean a mini environment and for particle measurement an online measurement. The isokinetic suction nozzle is in the working area and only the antistatic hose is led to the outside. The diameter of the hose varies depending on the manufacturer and device type (f³ or 100L). There are two typical sizes on the market: 10mm and 13mm.